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Arisure Closed System Transfer Devices enable the closed preparation and delivery of hazardous drugs from the Pharmacy to the Bedside.

Exposure to hazardous drugs during drug preparation, transportation, administration and disposal puts healthcare professionals at risk of developing adverse health effects.1

Up To 75%

of wipe samples from several hospitals have been found to be contaminated with at least one chemotherapuetic agent.2

Arisure Closed System Transfer Device

The National Institute for Occupational Safety and Health (NIOSH) recommends closed-system drug transfer devices1 to prevent the transfer of contaminants into the system and the escape of hazardous substances out of the system during drug preparation and administration.3

Arisure Closed System Transfer Devices provide a high level of clinical safety when preparing and administering chemotherapeutic and other hazardous drugs. Closed and needle-free, the system meets required standards and complies with guidelines for preventing contamination and promoting the safety of your healthcare workers and patients.

Arisure Devices

Arisure Closed
Vial Adaptor
Dry Spike
Arisure Closed
Male Luer Valve

Closed Vial Adaptor

Designed for use with ONE-LINK/CLEARLINK needle-free IV connectors

The Arisure Closed Vial Adaptor creates a mechanically and microbiologically closed system,4 thus helping to prevent hazardous drug exposure and maintaining medication sterility. Available to fit 13 mm, 20 mm and 28 mm liquid and powder vials for reconstitution.

Arisure Closed Vial Adaptor

Dry Spike

The Arisure Dry Spike enables closed injection into medication administration bags. Unlike other leading closed-system transfer devices, none of the components have needles, helping you to reduce the exposure of your healthcare teams to sharps.

Arisure Dry Spike

Closed Male Luer Valve

The Arisure Closed Male Luer Valve ensures closed transport and injection from a syringe or infusion from administration set. Designed for use with the ONE-LINK/CLEARLINK needle-free IV connectors, the Arisure Closed Male Luer Valve enables a dry disconnect for up to 10 actuations.

Arisure Closed Male Luer Valve

Arisure Features

Simple System - Fewer Components

simple system—Fewer components

Arisure Closed System Transfer Devices comprise just three components. Arisure Closed Male Luer Valve works with standard syringes and administration sets you have and does not require stocking additional syringes or sets.

Optimized Performance and Safety

Optimized Performance and Safety

Arisure Closed Male Luer ensures a dry disconnect from widely used ONE-LINK and CLEARLINK needle-free IV connectors for up to 10 actuations. It locks onto the syringe or administration set, ensuring easy setup and reducing sharps exposure.4

Patient and Staff Protection

Patient and staff protection

Arisure Closed System Transfer Devices will help you meet U. S. Pharmacopeia’s (USP’s) standards for safe handling of hazardous drugs, as set out in the proposed USP General Chapter <800>, expected to be introduced in December 2019.5

Rx Only. For the safe and proper use of the devices mentioned herein, please refer to the appropriate Instructions for Use or Operator’s Manual.


  1. NIOSH Alert. Preventing occupational exposure to antineoplastic and other hazardous drugs in health care settings. 2004. Available at https://www.cdc.gov/niosh/docs/2004-165/ pdfs/2004-165.pdf (accessed November 2017).
  2. Tilyou S. Cytotoxic drug residues still lurking in health care facilities. Pharmacy Practice News 2010;7(1). Available at http://forums.pharmacyonesource.com/phos/attachments/phos/pharmacy_ops/516/1/Cytotoxic/20Drug/20Residues.pdf (accessed November 2017).
  3. Nygren O. NIOSH Definition of Closed-System Drug-Transfer Devices. Ann Occup Hyg 2009;53(5):549.
  4. Data on file, Baxter Healthcare Corporation.
  5. USP. USP general chapter <800> hazardous drugs — handling in healthcare settings. Available at http://www.usp.org/compounding/general-chapter-hazardous-drugs-handlinghealthcare (accessed November 2017).